CBD FAQ Get answers to the most popular CBD questions

We interviewed Austin Flohrschutz, Director of Science for TruPotency, about the most popular CBD questions.

What are the side effects of CBD?

Many clinical trials show no side effects for CBD, but when they are reported the side effects tend to be very mild and many times the placebo group has almost as high or even the same side effects. Side effects that may happen include decreased/increased appetite, tiredness, and diarrhea. However, this should not be a concern for most people. 

Is it possible to overdose from CBD?

It would be very hard to overdose on CBD. Clinical trials have used 800 mg up to 1500 mg a day with no fear of overdosing. GW pharmaceuticals, the maker of a CBD seizure medication called Epidiolex, suggests an upper limit of 20 milligrams of CBD per kilogram of body weight per day (20 mg/kg). For a 150-pound person this would equate to about 1400 mg a day, but that does not mean that taking more means you are overdosing. However some studies have used up to 50 mg/kg which would make that 1400 mg turn into 3500 mg, an exceptionally high dose. There is some cause for concern with the liver with more information on below. 

Can you have a withdrawal from CBD?

There has been no withdrawal reported for CBD and it may even help with withdrawal symptoms from various drugs of abuse, such as alcohol and opioid abuse. 

Can you get addicted to CBD?

CBD is non-addictive and may actually be beneficial for those struggling with addiction. Pre-clinical and clinical trials have found no drug reinforcement properties associated with CBD. 

How does CBD help with drug/alcohol addiction?

There are a few different thoughts here, but one of the major aspects of quitting a drug of abuse is dealing with the withdrawal symptoms, including anxiety and intrusive thoughts associated with the substance. CBD seems to help reduce this anxiety and other withdrawal symptoms to help get past the first stage of quitting an abusive substance. 

CBD also seems to help with relapse for similar reasons. It helps to control mood and anxiety associated with drug use, so the thoughts of using the drug are not as strong or intrusive to your daily life. Emotional issues are one reason people will self medicate and become addicted, so if CBD will help someone manage anxiety or mood problems, then it can help avoid feeling the need to self medicate on dangerous substances.

Pain is also a common withdrawal symptom, especially associated with opioid withdrawal. CBD can help reduce this pain and help control normal every pain as well. There are many clinical trials currently for substance use disorders, so we are waiting to learn more. 

Can CBD cause liver damage?

There is a somewhat recent scare from a published study suggesting CBD causes liver toxicity. ProjectCBD has a great overview of why this study is flawed, but we can turn the alarm off about this subject. When converting from animal dosages to humans, the study used dosages where the lowest dose was at the upper end of recommendations for humans. The highest dose (2460 mg/kg) when converted is roughly 10 times the maximum recommended dosage for humans.

So they are using dosing that is unrealistic to a real world situation. Another point is that over the counter medications, like acetaminophen (Tylenol), can cause very severe liver failure at high dosages, yet are available to anyone at most stores, and not to mention alcohol and all the liver and other issues associated with that. 

There is some concern with the liver and CBD though. CBD can inhibit the breakdown of other medication you are taking, effectively increasing the amount of the drug in your body, which could then cause liver toxicity. This is the same reason some medications will tell you to avoid grapefruit juice. So if you are taking medications, like blood thinners, you should talk to your doctor about using CBD along with your medication, so they can monitor your health. 

Will CBD oil make me tired?

Most likely, CBD will NOT make you tired. Some people have reported this side effect at large doses, but generally speaking CBD is not similar to THC in this regard. CBD can help with sleep, but is not a sedative, like standard sleeping medications. CBD can help you rest easier if you have problems with anxiety and intrusive thoughts that keep you up at night or pain that keeps you from getting comfortable in bed. 

Will CBD oil help sciatica?

Although I am not aware of any studies specifically looking at sciatica, CBD may help with this type of pain, called neuropathic pain. One study suggests CBD helps with both neuropathic pain and anxiety relief though serotonin receptor activation. Another study suggest similar neuropathic relief in chemotherapy model of neuropathy. So, although there is nothing conclusive, the data is promising. 

Can CBD help lower blood pressure? If so, how?

CBD may help reduce blood pressure. You will see a common theme as to how CBD is working because we don’t really know how CBD is causing its effects. There are some hypotheses out there as to how CBD is interacting with the body, but no clear picture has been made yet.

What medications should you not take while on CBD?

MedlinePlus is a government website that shows CBD’s major medication interactions with Clobazam and Valproate along with other moderate/minor interactions. One study specifically looked at warfarin (a blood thinner), which may be a dangerous interaction as well. Drugs.com suggests a slightly larger list of 24 medication with major interactions, but check with your doctor and ask if you should avoid grapefruit juice while on your medications. If the answer is yes, then you should probably avoid CBD as well. 

How does CBD oil help with epilepsy?

Unfortunately, how CBD actually works is a bit of a mystery. There are some hypotheses out there as to how CBD is interacting with the body, but no clear picture has been made yet. GW pharmaceuticals (maker of the CBD medication for seizures called Epidiolex) even states this on their website in a section directed at doctors and healthcare professionals. 

Many pharmacologist and related researchers are working diligently to figure this out. However I do want to make the point that although we know how 99%+ drugs work, there is one very common drug most people have used that we have no clue how it is working: acetaminophen (Tylenol). So just because we don’t know exactly how a drug is working, doesn’t mean we can’t or shouldn’t use it. 

How do CBD topicals work?

CBD is thought to help with skin due to its anti-inflammation and antioxidant properties. So it can be good for overall skin health, but has been looked at for certain skin ailments like psoriasis.

For facial use, CBD has been suggested to inhibit the sebum production of sebocytes. Sebum is a form of oil and overproduction can exacerbate acne. So reduced oil along with anti-inflammatory properties can help improve acne. CBD facial skincare products might start to become a more popular for daily facial care routines. 

Topical CBD is probably not getting through the skin at any appreciable level, so while oral CBD might be good for anxiety, topical CBD won’t really be affecting your brain. Enough can potentially get through for local pain and inflammation relief, so creams or balms may be beneficial to some. Though there are transdermal products, which are designed with skin penetration enhancers to assist in delivering CBD (or other drugs) into the body through the skin. 

Can CBD oil help with diverticulitis?

Although I am not very familiar with this disease, it seems to be heavily associated with inflammation. CBD can help with the inflammation, but I would not say it would be a treatment or cure for diverticulitis. Check with your doctor as they might prescribe antibiotics or other treatments for this. 

Will CBD oil help with idiopathic pulmonary fibrosis?

This is another disease I am not very familiar with, but CBD might help with inflammation associated with the disease, although by no means does that suggest a cure. There are two somewhat new medications currently available to those who suffer with IPF, so check with your doctor to see if those may be a choice for you. 

Is full spectrum CBD better than broad spectrum or isolate-based CBD? If so, why?

I always recommend full-spectrum CBD products. However consuming small amounts of THC can be an issue for some people, either because they are very sensitive to THC or they have to take drug tests. Generally speaking though, the closer you get to the full plant extract the greater enhancement from the entourage effect you will have for therapeutic potential. Ethan Russo wrote an updated article on the entourage effect in 2019 that is a great read. 

Broad-spectrum is close to full spectrum and you will probably still get some synergistic, but not quite as potent as full-spectrum. From a therapeutic potential aspect CBD isolate probably has the least benefits all alone, but still is a very fine molecule that can help children reduce their daily seizures and improve their quality of life.

Where can you get high quality CBD products?

With over 1000 new CBD brands created in 2019 it is hard for consumers to know if a company is legitimate or just jumping on the CBD hype bandwagon to make a quick buck. TruPotency has assembled a diverse science advisory board of PhD scientists, doctors, and wellness professionals to push the boundaries of our scientific understanding.

Our common thread is the study of cannabinoids and drug interactions within the body. From neuroscience, to cancer research, to dermatology, and plant microbiology, our collective goal is to use our knowledge to bring you the purest, most effective and safe cannabinoid products.

It’s not just about making sure a bottle has the labeled amount of cannabinoids. It’s also about testing for pesticides that could come from questionable growing practices, heavy metals from bad extraction techniques, and molds that can show up in organic material. No one has been willing to be a watchdog, so we are motivated to take on this task.

Best Ways to Consume CBD

June 25, 2020

Cannabidiol (CBD) is gaining more and more popularity due to its anti-inflammatory, anti-anxiety, anti-spasmodic effects, along with many other health-promoting properties. There are many ways to consume CBD, which can be overwhelming and sometimes confusing. Here we’ll discuss the pros and cons of the most popular ways to consume CBD. Jump to:Ways to Consume CBD…

Delta-8 THC Chocolates Recipe

August 17, 2020

Delta-8 THC is not the same substance as Delta-9 THC. We recommend learning more about Delta-8 THC before trying it. In addition to reading up, we always recommend you consult with your doctor before consuming any new substances. If you are new to Delta-8 THC, check out our review of the best Delta-8 THC brands.

How to Press CBD Flower into Rosin

September 29, 2020

Author: Jason Beverly Rosin is a popular type of concentrate that is solventless, and it is used with heat and pressure to squeeze or extract the concentrate from the plant or flower you are using. This extraction technique has been used for many years, and is very popular for CBD flower rosin. CBD flower rosin…

4 Surprising Reasons You Might Consider CBD Products

June 1, 2020

Author: Jason Beverly The human body was created to be magical. There’s still a lot for us to understand about how our bodies are designed to function. As more studies and research about the human body takes place, people are gaining more insights about it. We are continuously learning how to treat some of the…

Turmeric & CBD Benefits

April 22, 2020

If you suffer from pain, anxiety, and other chronic ailments, chances are you’ve heard of, or have even tried Cannabidiol (CBD) oil. But did you know that turmeric contains similar therapeutic properties as CBD oil? In fact, more and more CBD companies are combining these two therapeutic compounds together. Why? The truth is, when combining…

Delta-8 THC Chocolate Chip Cookies Recipe

June 20, 2021

Delta-8 THC is not the same substance as Delta-9 THC. We recommend learning more about Delta-8 THC before trying it. In addition to reading up, we always recommend you consult with your doctor before consuming any new substances. If you are new to Delta-8 THC, check out our review of the best Delta-8 THC brands.…

Tips on How to Find and Choose Vegan CBD Products

March 11, 2020

Author: Jason Beverly CBD is a booming industry, and this is great for consumers. Never before have we had so many different vegan CBD products to help us live healthier and happier lives. With so many different producers and products on the market, let find some great vegan CBD products with this vegan CBD buying…

Does CBD Oil Thin Your Blood?

January 26, 2022

Author: Jason Beverly In recent years the popularity and therapeutic appeal of CBD have grown a significant amount, with many people turning to CBD oils and CBD-infused products for relief from a wide variety of conditions, including anxiety, epilepsy, and chronic pain. While CBD may help to ease the symptoms associated with these conditions, it…

CBD Chocolate Chip Cookies Recipe

November 27, 2019

Note: CBD loses it’s potency if it’s heated at 320 degrees F or above. Therefore, we never bake CBD above 300 degrees F. CBD used in this Recipe We love baking with the 1000mg Nanocraft CBD Tincture. It’s broad spectrum and works great. Shop Nanocraft CBD CBD Chocolate Chip Cookies FAQ Do CBD cookies get…

Why CBD?

December 28, 2019

So why did I start this journey?  My son started a company, he’s an entrepreneur, a word that is foreign to my generation.  He’s always been one step ahead in thinking than any of us.  He comes up with things that we have always said, “gee I wish I would have thought of that, and…